In 1616 a monk from Kazan Nifont founded the Transfiguration, now the Holy Trinity Monastery on the bank of the Tura River. By the strength of three monks and peasant assistants, a wooden Spaso-Preobrazhenskaya church, cells for monks and hegumen were placed on a high promontory. By the beginning of the XVIII century the church burned down and the monastery fell into decay. The revival of the monastery in Tyumen is connected with the Metropolitan of Tobolsk Philotheus, who obtained permission from Peter the Great to build a stone cathedral and even received money from the treasury. Philotheus was born in Ukraine and attracted the Kiev master hands for the construction of the cathedral, so the cathedral was built in the style of the Ukrainian baroque. Five-domed Trinity Cathedral was opened in 1715.
From 1923 to 1995 the Holy Trinity Monastery was closed. Now the cathedral has been undergoing the reconstruction. It also stores а reliquary with the relics of Metropolitan Philotheus, secretly buried under Soviet rule, and this saved them from destruction. They started building the cruciform Peter and Paul Church on the territory of the monastery in 1726 and finished in 1755. After its closure in 1923 the building was given to the regional museum. A monument to Metropolitan Philotheus has been standing in the square of the monastery since 2007.